Behr, Pascal, Dr.
ETH Zürich
PhD Thesis 2015
Current Research
- FluidFM Technology: Force controlled liquid manipulation system for biomedical applications (e.g. Single Cell Experiments)
- Implementation of a Scanning Ion Conductance Microscope (SICM) based on FluidFM Technology
- Development of an automated Patch Clamping System using FluidFM Technology
- Fabrication of hollow AFM cantilevers using polymeric materials
Start-up Company
Co-Founder of Cytosurge Inc Cytosurge is an ETH Spinoff Company aimed at commercializing FluidFM Technology.
For more information please visit the official website at external page www.cytosurge.com.
Publications
- external page Force-controlled patch clamp of beating cardiac cells
D. Ossola, M.-Y. Amarouch, P. Behr, J. Vörös, H. Abriel and T. Zambelli
Nano Letters, 2015, 15 (3), pp 1743–1750, doi: 10.1021/nl504438z - external page Cooperative Vaccinia Infection Demonstrated at the Single-Cell Level Using FluidFM
P. Stiefel, F. I. Schmidt, P. Dörig, P. Behr, T. Zambelli, J. A. Vorholt, J. Mercer
Nano Letters, 2012, 12 (8), pp 4219–4227 - external page Force-controlled spatial manipulation of viable mammalian cells and microorganisms by means of hollow AFM cantilevers
P. Doerig, P. Stiefel, P. Behr, E. Sarajlic, D. Bijl, M. Gabi, J. Vörös, J. Vorholt, T. Zambelli
Appllied Physics Letters, 97, 023701 (2010); - external page FluidFM: Combining Atomic Force Microscopy and Nanofluidics in a Universal Liquid Delivery System for Single Cell Applications and Beyond
A. Meister, M. Gabi, P. Behr, P. Studer, J. Vörös, P. Niedermann, J. Bitterli, J. Polesel-Maris, M. Liley, H. Heinzelmann, T. Zambelli
Nano Letters , 2009, 9 (6), pp 2501–2507 - external page Nanoscale dispensing in liquid environment of streptavidin on a biotin-functionalized surface using hollow atomic force microscopy probes
A. Meister, J. Polesel-Maris, P. Niedermann, J. Przybylskaa, P. Studer, M. Gabi, P. Behr, T. Zambelli, M. Liley, J. Vörös, H. Heinzelmann
Microelectronic Engineering , Volume 86, Issues 4-6, April-June 2009, Pages 1481-1484
Oral Presentations
- Combining AFM with hollow cantilevers for electrophysiological measurements
P. Behr, D. Ossola, P. Doerig, P. Stiefel, M. Gabi, E. Sarajlic, D. Bijl, J. Vörös, T. Zambelli
ISPM 2010, Sapporo, Japan, May 12, 2010 - FluidFM: A novel AFM-based tool for single cell experiments
P. Behr, M. Gabi, A. Meister, M. Liley, J. Przybylska, P. Studer, H. Heinzelmann, J. Vörös, T. Zambelli;
WACBE World Congress on Bioengineering 2009, 26 – 29 July 2009; The Hong Kong Polytechnic University, Hong Kong - AFM-controlled injection of labelled molecules into single living cells
P. Behr, M. Gabi, P. Studer, A. Meister, M. Liley, J. Przybylska, H. Heinzelmann, J. Vörös, T. Zambelli;
ESF Conference on Nanomedicine, San Feliu de Guixols, Spain, September 2008
Poster Presentations
- Combining AFM with hollow cantilevers for electrophysiological measurements
P. Behr, D. Ossola, P. Dörig, E. Sarajlic, D. Bijl, M. Gabi, H. Abriel, J. Vörös, T. Zambelli
AFM BioMed 2010, 12-15.05.2010, Rovinj, Croatia - Controlled displacement of mammalian cells and microorganisms by FluidFM technology
P. Dörig, P. Stiefel, E. Sarajlic, D. Bijl, P. Behr, M. Gabi, J. Vörös, J. Vorholt, T. Zambelli
AFM BioMed 2010, 12-15.05.2010, Rovinj, Croatia - FluidFM Technology: A novel AFM-based tool for single cell experiments and beyond
P. Behr, M. Gabi, A. Meister, M. Liley, J. Przybylska, P. Studer, H. Heinzelmann, J. Vörös, T. Zambelli;
ESB 2009 - 22nd European Conference on Biomaterials, 07-11.09.2009, Lausanne, Switzerland - FluidFM: A novel AFM-based tool for single-cell experiments
P. Behr, M. Gabi, A. Meister, J. Polesel-Maris, P. Niedermann, J. Przybylskaa, P. Studer, M. Liley, J. Vörös, H. Heinzelmann, T. Zambelli
7th International Symposium on Scanning Probe Microscopy in Life Sciences, Oct. 8-9 2008, Berlin, Germany - AFM-controlled injection of labelled molecules into single living cells
P. Behr, M. Gabi, A. Meister, J. Polesel-Maris, P. Niedermann, J. Przybylskaa, P. Studer, M. Liley, J. Vörös, H. Heinzelmann, T. Zambelli
ESF-UB Conference in Nanomedicine 2008, September 19-24 2008, Hotel Eden Roc, Sant Feliu de Guixols, Spain - AFM-controlled injection of labelled molecules into single living cells under physiological conditions
P. Behr, M. Gabi, A. Meister, J. Polesel-Maris, P. Niedermann, J. Przybylskaa, P. Studer, M. Liley, J. Vörös, H. Heinzelmann, T. Zambelli
3rd International Workshop on Approaches to Single-Cell Analysis, September 11th & 12th 2008, ETH Zurich
Awards
- external page ZKB Technopark Pioneer Award, Ausgezeichnet für ihre wegweisende Entwicklung und pionierhafte Markteinführung der FluidFM®-Technologie.
03.04.2012, Zurich, Switzerland - MRC Poster Award 2010, Controlled displacement of mammalian cells and microorganisms by FluidFM technology
AFM BioMed 2010, 12.5.-15.05.2010, Rovinj, Croatia - Best Poster Award, Hollow AFM Probes Designed for Nanoscale Dispensing of Material in a Liquid Environment for Applications in Life Science
7th International Symposium on Scanning Probe Microscopy in Life Sciences, Berlin, October 2008, poster in collaboration with CSEM Neuchâtel
Patents
- Touch-screen based scanning probe microscopy (spm), 2013,
M. Gabi, P. Behr, S. Jud, J. Wolf, C. Weber, PCT/EP2013/000716 - Method for spatially manipulating a microscopic object and device for conducting said method, 2010,
Gabi M., Behr P., Dörig P., Zambelli T., Vorholt- Zambelli J., Stiefel P., Vörös J., PCT/CH2011/000020 - Device consisting of a channeled cantilever and a channeled probe holder, 2009,
Gabi M., Zambelli T., Behr P., Vörös J., PCT/EP2009/005393
Previous Research
- Master Thesis Towards advanced single walled carbon nanotube pressure sensors: electrical and mechanical investigations
Micro- and Nanosystems Group, ETH Zurich Supervisors: Prof. Dr. Ch. Hierold, MSc ETH Thomas Helbling - Semester Thesis II Development of a 2D Monte Carlo Simulation Toolbox using Comsol Multiphysics and Matlab
external page Bio-Inspired Sensors and Optoelectronics Laboratory, Northwestern University USA Supervisors: Prof. Dr. H. Mohseni USA, Prof. Dr. Andreas Schenk ETH - Semester Thesis I Fabrication Process for broad area laser diodes
Institut for Electronics IFE, ETH Zurich Supervisors: Prof. Dr. H. Jaeckel, Dr. H.-J. Lohe
Education
2002-2007 Master of Science in Electrical Engineering, ETH Zürich
- Focus on Opto- and Microelectronics
- Research in the Field of Micro- and Nanosystems
- Exchange Semester at Northwestern University USA, Jan-Jul 2006
- Board Member of EESTEC LC Zurich
1995-2002 Matura, Type C, Kantonsschule Zürcher Unterland KZU