Rajendran, Prayanka, Dr.

Rajendran, Prayanka

ETH Zürich
PhD Thesis 2015

Research Interests

The goal of my PhD thesis is to develop a novel sensing technique for single-cell mRNA/miRNA level studies using plasmonic nanoparticles. Even though PCR and microarrays have already become standard methods for the analysis of nucleic acids still more direct and less cumbersome assays are needed to make a breakthrough for direct oligonucleotide detection technology.

Rajendran, Prayanka
Figure- Schematics of the assay with gold nanoparticles. Upon target binding the gold nanoparticles gets close to each other generating a new mode in their scattering spectra.

Publications

Microspectroscopic analysis of green fluorescent proteins infiltrated into mesoporous silica channels
Ma, Y; Rajendran, P; Blum, C; Cesa, Y; Gartmann, N; Brühwiler, D and Subramaniam, V
Journal of Colloid and Interface Science, 356(1):123-130.

Conferences

Microwell arrays for direct quantification of oligonucleotides using plasmonic nanoparticles
P. Rajendran, M. Zenobi-Wong, J. Vörös
Elsevier-Label Free Technologies, 1.3 November 2012, Amsterdam, The Netherlands.
This poster received the "Best Poster Award".

Direct oligonucleotide quantification by sequence-specific gold nanoparticle assay in microwell arrays
P. Rajendran, Z.Wong, J. Vörös
8th NanoBio Europe 2012, 18.-20. June, Varese, Italy

Gold nanoparticle sensors for direct oligonucleotide detection in microwells.
P.Rajendran, J. Vörös and Z.Wong
Nanoplasmonic Sensors and Spectroscopy, 18.-22. Sept. 2011, Göteborg, Sweden

Gold nanoprobes for direct oligonucleotide detection.
P.Rajendran, J. Vörös and Z.Wong
Particles 2011- Stimuli Responsive Particles and Particle Assemblies 2011.

Direct oligonucleotide quantification by sequence specific gold nanoparticle assay.
P.Rajendran, J. Vörös and Z.Wong
Material Research Society Spring Meeting 2011, San Francisco.

Education

Master of Science in Photonics, 2007-2009
Ecole Normale Supeireure de Cachan, Paris,(France)
Wroclaw University, Wroclaw (Poland)

Bachelor of Technology, Industrial Biotechnology, 2003-2007
Anna University, India

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