Weydert, Serge

• organizing cultured neurons in well defined patterns and circuits
• short-term memory management in the hippocampus
• The brain, it's role and functioning is one of the grand topics in philosophy, biology and engineering. How do we think? How do we feel? How do we remember? Like many other researchers around the world we at LBB are eager to understand the nervous system. We are especially interested in examining elementary functions and processes of single neurons and want to understand how the puzzle pieces fit together. In neuroscience this is understood as the "bottom-up approach". Following this philosophy, I am working on microtechnological and microfluidical tricks, use small currents and dynamic surface modifications to control the position of cultured neurons and the growth of their axons.

external page “Brains on a chip”: Towards engineered neural networks S. Weydert, M. J. Aebersold, H. Dermutz, C. Forró, G. Thompson-Steckel, J. Vörös, L. Demkó, Trends in Analytical Chemistry (2016) DOI: 10.1016/j.trac.2016.01.025

external page Controlled single-cell deposition and patterning by highly flexible hollow cantilevers V. Martinez, C. Forró, S. Weydert , M. J. Aebersold, H. Dermutz, O. Guillaume-Gentil, T. Zambelli, J. Voros, L. Demkó, Lab on a Chip (2016) DOI: 10.1039/C5LC01466B

external page Easy to Apply Polyoxazoline-Based Coating for Precise and Long-Term Control of Neural Patterns S. Weydert, S. Zürcher, S. Tanner, N. Zhang, R. Ritter, T. Peter, M. J. Aebersold, G. Thompson-Steckel, C. Forró, M. Rottmar, F. Stauffer, I. A. Valassina, G. Morgese, E. M. Benetti , S. Tosatti, J. Vörös, Langmuir (2017) DOI: 10.1021/acs.langmuir.7b01437

S. Weydert, H. Dermutz, L. Demko, C. Forro, J. Chaaban, J. Vörös, "Engineering Elementary Memory Circuits", SfN Annual Meeting, Washington, November 2014. Poster Presentation

S. Weydert, H. Dermutz, H. Han, M. J. Aebersold, C. Forro, G. De Bruyne, L. Demko, T. Zambelli, J. Vörös, "Writing Single Axon Paths in situ", AXON 2015, Klosterneuenburg, Austria, September 2015. Poster Presentation

S. Weydert, H. Dermutz, H. Han, M. J. Aebersold, C. Forró, L. Demkó, T. Zambelli, J. Vörös, "Building Networks with Single Neurons", Nanobiotech 2015, Montreux, Switzerland, November 2015. Poster Presentation

S. Weydert, G. Thompson-Steckel, A. Renz, M. J. Aebersold, V. Martinez, C. Forró, K. Tybrandt, H. Dermutz, H. Han, T. Zambelli, J. Vörös "Tools for defined networks on multielectrode arrays", MEA Meeting 2016, Reutlingen, Germany, June 2016. Poster Presentation

S.Weydert, T.Peter, S.Tanner, S. Zürcher, S. Tosatti, M. J. Aebersold, G. Thompson-Steckel, J.Vörös "Novel polymer coatings improve cell patterning quality and stability", Biointerfaces, Zurich, Switzerland, August 2016