Clément, Blandine
Blandine Clément
location: GLC F 18
email:
Inst. f. Biomedizinische Technik
Gloriastrasse 37/ 39
8092 Zürich
Switzerland
Student projects
Feel free to contact me if you are interested in a student project (preferably Master Thesis). I am constantly looking for highly motivated students who want to work in the field of bottom-up neuroscience. Just send me an email including your CV, an overview of your courses and a short statement about your motivation as well as your skills/experiences. The project can involve both, working in the lab conducting experiments and collecting data as well as purely data analysis driven. Together we can fine tune according to your individual preferences.
Research Interests
- Bottom up neuroscience
- Biohybrid systems
- Microphysiological systems and 3D cell cultures
- Nociception
- Safety pharmacology and drug discovery
Publications
external page An implantable biohybrid nerve model towards synaptic deep brain stimulation
L. Sifringer, A. Fratzl, B.F. Clément, P. Chansoria, L. Mönkemöller, J. Duru, S.J Ihle, S. Steffens, A. Beltraminelli, E. Ceylan,J. Hengsteler, B. Maurer, S.M Weaver, C.M. Tringides, K. Vulić, S. Madduri, M. Zenobi-Wong, B. Roska, J. Vörös, T. Ruff
2024 DOI: external page10.1101/2024.05.31.596665
external page Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings
Girardin, S., Clément, B. F., Ihle, S. J., Weaver, S., Petr, J. B., Mateus, J. C., Duru, J., Krubner, M., Forró, C., Ruff, T., Fruh, I., Müller, M., Vörös, J.
Lab on a Chip 2022, DOI: 10.1039/D1LC01110C
external page Engineering an in vitro retinothalamic nerve model
G. Amos, S.J. Ihle, B.F. Clément, J. Duru, S. Girardin, B. Maurer, T. Delipinar, J. Vörös, T. Ruff
Frontiers in Neuroscience 2024 DOI: 10.3389/fnins.2024.1396966
external page Effects of a soft robotic exosuit on the quality and speed of overground walking depends on walking ability after stroke
Sloot, L. H., Baker, L. M., Bae J., Porciuncula F., Clément B. F., Siviy, C., Nuckols, R., W., Baker, T., Sloutsky, R., Choe, D. K., O’Donnell K., Ellis T D., Awad, L. N., & Walsh C. J.
Journal of NeuroEngineering and Rehabilitation 2023, DOI: 10.1186/s12984-023-01231-7
Oral presentations
Nerve model to study the diverse electrophysiological properties of human iPSC-derived nociceptive neuron subtypes
Clément, B. F., Ruff, T., Petrella, L., Duru, J., Tringides, C. M., Vörös, J.
4th In-Vitro 2D & 3D Neuronal Networks Summit, Zürich , 8 - 10 April 2024, selected short talk
Nerve model to study the diverse electrophysiological properties of human iPSC-derived sensory neuron subtypes
iPSZurich Symposium, Zürich , 4 -5 April 2024, selected short talk
This talk received the best oral presentation award.
Development of 3D hydrogel-based in vitro circuits with cocultures of human sensory neurons and Schwann cells
Clément, B. F., Tringides, V. Dranseika, C. M., Duru, J., Ruff, T., Vörös, J.
MRS Fall Meeting 2023, Boston, MA, USA, 26 - 30 November 2023, selected short talk.
Posters
Towards 3D hydrogel-based cocultures of human sensory neurons and Schwann cells in microchannels
Clément, B. F., Tringides, V. Dranseika, C. M., Duru, J., Ruff, T., Vörös, J.
NanoBioTech Montreux, Montreux, Switzerland, 13 - 15 November 2023
This poster won the Discovery Award for high potential research
Development of hydrogel-based 3D in vitro neuronal networks
Clément, B. F., Tringides, C. M., Duru, J., Ruff, T., Labouesse, C., Garau Paganella, L., Deshmukh, D., Tibbitt, M., Vörös, J.
MPS World Summit 2023, Berlin, Germany, 26 - 30 June 2023
Stimulation-induced response as biomarker for sensory neuron subtypes on a CMOS-based nerve model
Clément, B. F., Ruff, T., Petrella, L., Duru, J., Tringides, C. M., Vörös, J.
Cambridge Bioelectronics Symposium, Cambridge, UK, 15 - 16 June 2023
This poster won the Best Poster Award
Towards the development of a nerve-on-a-chip platform for studying peripheral neuropathies in vitro
Clément, B. F., Ruff, T., Sifringer, L., Girardin, S., Weaver, S., Vörös, J.
Biointerfaces International, Zürich, Switzerland, 13 - 15 September 2022
Engineering a stretchable nerve-on-chip platform to study the changes in nerve conduction under tension in vitro
Clément, B. F., Ruff, T., Sifringer, L., Girardin, S., Weaver, S., Vörös, J.
FENS 2022, Paris, France, 9 - 13 July 2022
Toward the development of a stretchable nerve-on-chip platform to study the role of tensile stress in peripheral neuropathies in vitro
Clément, B. F., Ruff, T., Sifringer, L., Girardin, S., Weaver, S., Vörös, J.
MEA Meeting 2022, Tübingen, Germany, 5 - 8 July 2022
Stretchable nerve model for studying peripheral neuropathies in vitro
Clément, B. F., Ruff, T., Sifringer, L., Steffens, S., Razzoli, M., Vulić, K., Vörös, J.
NanoBioTech-Montreux Conference 2021, Montreux, Switzerland, 15 - 17 November 2021
Supervised Students in Projects
A compartmentalised culture of human nociceptors and human keratinocytes to model peripheral pathophysiological conditions in vitro
Claire Zhang, Master's thesis, Feb - Aug 2024
Towards nociceptor subtype identification via chemical compounds on a CMOS-based nerve model
Lea Wallimann, Bachelor's thesis, Spring semester 2024
Electrophysiological characterization of sensory neuron and Schwann cell coculture
Timothy Kurer, Semester project (co-supervised by Christina Tringides), Spring semester 2024
Optimization of a 3D hydrogel-based nerve-on-chip platform
Cédric Pfister, bachelor's thesis (co-supervised by Christina Tringides), Fall semester 2023
Investigation of stimulation-induced response of sensory neurons on a CMOS-based nerve model
Lorenzo Petrella, semester project (co-supervised by Tobias Ruff), Spring semester 2023
Feasibility and characterization of growing neurons in 3D
Enrique Cifuentes Cassalett, semester project (co-supervised by Christina Tringides), Spring semester 2023